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Award Winning Oils. Medical Grade Formulations.
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Understanding cannabinoids, and the mechanisms between THC:CBD


CBD acts to regulate the binding of THC, and by moderating the affinity of THC, can reduce side affects associated with its psychoactivity.


(Left) first and last line on this place demonstrate a 0:1, cbd:thc ratio, while the middle lanes are a 1:1 ratio.

(right) cbd and thc are both present. lane 1 indicates a 1:1 cbd:thc ratio, where as the last lane shows a 1:3 cbd:thc ratio.

Cannabinoid analysis and research credit alpha-cat Research Team.

1:0 THC:CBD

strong euphoric psychotropic effects

1:1 CBD:THC

Desired Effect - restoration of tranquility and relaxation.

Applicable to : Appetite Stimulation, Autism, Fibromyalgia, Severe Pain, Skin conditions

3:1 CBD:THC

Desired Effect - Recovery, and reduction of auto-immune conditions:

Applicable to : auto immune diseases, breast cancer, chron’s disease/Colitis, extreme arthritis, IBS, MS

Pain and Inflammation, psoriasis

20:1 CBD:THC

Desired Effect - Relief

Targets neurological issues : anxiety, cerebral palsy, depression, epilepsy, mild arthritis, parkinson’s, restless leg syndrome, phantom pain.

ARTICLE & DATA COURTESY OF ALPHA-CAT. FOR MORE INFORMATION, PLEASE CONSULT PUBMED, MEDICAL JANE, PROJECTCBD, AND CBD.ORG


Case Study : Cannabidiol in anxiety and sleep

Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in anxiety and sleep: A large case series. Perm J 2019;23:18-041. DOI: https://doi.org/10.7812/TPP/18-041


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ECS : Endocannabinoid System

A system of natural receptors, enzymes, and endocannabinoids.

Endo - endogenous : naturally occuring

CB1 : CNS (brain, nerves of spinal cord)

CB2 : PNS (immune system, nerves at extremities, digestive function)

Through these receptors, the body maintains homeostasis by regulating :

appetite, digestion, immune function, inflammation, neuroinflammation, mood, sleep, reproduction/fertility, motor control, temperature regulation, memory, pain, pleasure/Reward.

Article - The Endocannabinoid system as an emerging target of pharmacology.

PMCID : PMC2241751

NIHMSID : NIHMS38123

PMID : 16968947


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Cannabis, Pain, and Sleep: Lessons from Therapeutic Clinical Trials of Sativex, a Cannabis-Based Medicine

By Ethan B. Russo, Geoffrey W. Guy, and Philip J. Robson

GW Pharmaceuticals, Porton Down Science Park, Salisbury, Wiltshire SP4 OJO, UK.


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CBD Provides Long Lasting Protection against the deleterious effects of inflammation in a viral model of MS. A role for A2A receptors.

Publication : Neurobiology of Disease.

Author : M. Mecha,A. Feliú,P.M. Iñigo,L. Mestre,F.J. Carrillo-Salinas,C. Guaza


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Cannabis Dosing Explained

Article by Project CBD director, Martin A Lee.

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Cannabis, a complex plant : Different Compounds and Different Effects on Individuals.

Article - NCBI

PMCID : PMC3736954

PMID : 23983983


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A User’s Guide to Cannabinoid Therapies in Oncology

Article : PubMed NBCI

PMCID : PMC5176373

PMID : 28050136

by V. Maida, MD MSc BSc and P.J. Daeninck, MD MSc


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Cannabis-based Medicines for Chronic Neuropathic Pain in Adults

Article by NCBI

Author : Mücke M1, Phillips T, Radbruch L, Petzke F, Häuser W.


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Cannabis in the Treatment of Epilepsy: Hard Evidence at Last?

Article - NCBI

PMCID : PMC5767492

PMID : 29344464

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Review of the Neurological Benefits of Phytocannabinoids

Article NCBI :

PMCID : PMC5938896

PMID : 29770251

By Joseph Maroon & Jeff Bost


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CBD:THC Ratios : Maximizing Your Medicine

Content Courtesy of The Apothecarium.

Cited : NCBI, PubMed

By Cameron Klar


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CBD Drug Interactions: Role of Cytochrome P450

Content Courtesy of Project CBD.

Citation : PubMed, NCBI

By : Adrian Devitt-Lee


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Cannabidiol Reduces Cigarette Consumption in Tobacco Smokers : Preliminary Findings

By : Celia J.A. Morgan ⁎, Ravi K. Das, Alyssa Joye, H. Valerie Curran, Sunjeev K. Kamboj

Clinical Psychopharmacology Unit, University College London, London, UK


Content courtesy of leafly holdings.  

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Cannabis, Terpenes & Flavinoids

Main Terpenes found in todays Cannabis.

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Linalool

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Limonene

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Terpinolene

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Humulene

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Octimene

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alpha Pinene

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Caryophyllene

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